Penetration Process of a Hydrated Deep Eutectic Solvent Through the Stratum Corneum and its Application as a Protein Penetration Enhancer
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چکیده
منابع مشابه
Influence of Dimethyl Sulfoxide as a Penetration Enhancer of Piroxicam Gel Through Biological Skin
Piroxicam is a non-steroidal anti-inflammatory agent which has an extensive use in rheumatic disorders. Since its skin penetration is still a subject for research, the aim of this study was to evaluate the effect of dimethyl sulfoxide on percutaneous penetration of piroxicam gel formulation through skin. In this study, as a model, two types of 0.5% piroxicam new gels, so called red and gr...
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It is preferred that topically administered drugs act either dermally or transdermally. For that reason they have to penetrate into the deeper skin layers or permeate the skin. The outermost layer of the human skin, the stratum corneum, is responsible for its barrier function. Most topically administered drugs do not have the ability to penetrate the stratum corneum. In these cases modulations ...
متن کاملinfluence of dimethyl sulfoxide as a penetration enhancer of piroxicam gel through biological skin
piroxicam is a non-steroidal anti-inflammatory agent which has an extensive use in rheumatic disorders. since its skin penetration is still a subject for research, the aim of this study was to evaluate the effect of dimethyl sulfoxide on percutaneous penetration of piroxicam gel formulation through skin. in this study, as a model, two types of 0.5% piroxicam new gels, so called red and green ge...
متن کاملStructure Enhancement Relationship of Chemical Penetration Enhancers in Drug Transport across the Stratum Corneum
The stratum corneum is a major barrier of drug penetration across the skin in transdermal delivery. For effective transdermal drug delivery, skin penetration enhancers are used to overcome this barrier. In the past decades, a number of research studies were conducted to understand the mechanisms of skin penetration enhancers and to develop a structure enhancement relationship. Such understandin...
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Corresponding Authors: Kiran Sharma II E 96 / A, Nehru nagar, Ghaizabad, 201001, U.P. Email id: [email protected] Abstract: Skin penetration enhancers are the most commonly used approach for enhancing drug penetration into the skin through transdermal drug delivery system or topical administration. These skin penetration enhancers are molecules which reversibly remove the barrier resistance...
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ژورنال
عنوان ژورنال: ChemistryOpen
سال: 2020
ISSN: 2191-1363,2191-1363
DOI: 10.1002/open.202000114